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Clinical Research Services

This REACT Center provides expertise related to the design and implementation of clinical research. This includes, but is not limited to the services described in this page.

To request more information about the services listed below or if you need a service not listed here, please contact us or call (205) 934-9211.

Bionutrition Core

Assists with planning and designing the nutritional components of research protocols and can assist with implementing the protocol, recruitment/screening of research participants, and data collection and analysis of dietary intake. Its metabolic kitchen provides specially designed meals for participants on both inpatient and outpatient studies to meet protocol requirements.

Center for AIDS Research Behavioral and Community Sciences Core

Supports research on behavioral, environmental, economic, and social HIV risk and protective factors in the Deep South. It aims to bring methodological advances in behavioral and community science to bear on HIV research and interventions in Deep South communities disproportionately affected by the shifting epidemic.

Clinical Research Support Program

This program provides a pool of trained, certified research coordinators to assist with study implementation, including interpretation and adherence to regulatory requirements, organizational and budget management, communication with sponsors, internal quality measures, and data management. Resource pooling provides flexibility and limits the need for individual investigators or programs to overstaff to handle sporadic needs. This program also offers the services of the Neuromuscular Function Laboratory and the Cardiorespiratory Function Laboratory.

Clinical Research Unit

Committed to providing investigators and their teams a research environment and broad range of services guided by good clinical practice. This contributes to the conduct of excellence in clinical and translational research. The unit equips investigators with essential tools and critical resources, while providing a highly efficient and flexible infrastructure that is sustainable through a comprehensive cost-recovery system.

Exercise Clinical Trials Facility

This 7,000 square foot core facility is well-equipped to provide a clean, safe, and user friendly exercise training and testing environment for supervised exercise clinical trials, and contains two laboratories for a wide array of human physiological and performance tests.

Experimental Biomechanics Core

This core provides investigators with state-of-the-art equipment and trained personnel to facilitate mechanical testing and measurement of mechanical properties of biological and man-made materials, structures, and constructs.

Heflin Center Genomics Core Lab

The Heflin Genomics Core offers genetic and genomic services including single nucleotide polymorphism detection, standard Sanger Sequencing and Next-Generation sequencing for multiple assays. The Next-Generation assays include whole exome profiling, whole transcriptome profiling, microRNA sequencing, Methylation sequencing, custom capture and sequencing, and microbiome/metagenomic sequencing.

Human Imaging Shared Facility

Provides standardized imaging support of human cancer studies, leading to recognition as a NCI qualified Center of Quantitative Imaging Excellence. The core provides radiology expertise for: 1) standardized protocol review, 2) state-of-the-art image acquisition, 3) standardized tumor metrics quantification and response assessment for all imaging modalities (e.g., CT, MRI, Ultrasound, PETCT and PETMR), and 4) development and implementation of new analysis tools and techniques for the UAB Comprehensive Cancer Center’s clinical and translational research studies.

Human Physiology/Metabolism Core Laboratory

Provides analysis of hormones, adipokines, markers of inflammation, glucose, lipids, and other molecules relevant to risk for obesity and chronic metabolic disease for both clinical and animal studies, and from both biological fluids and tissue culture specimens.

International Neuroimaging Laboratory

Houses a research-dedicated Siemens Prisma 3T whole body scanner for structural and functional brain and body imaging, MRI preparation rooms and interview rooms for pre- and post-scan patient monitoring and testing, and a fully-equipped experimental suite for behavioral and physiological recording.

Kinomics Core

Kinomics is the study of kinase signaling within cellular or tissue lysates. The Kinomics Core can help elucidate cellular signaling pathways altered by treatment (i.e. drug or condition change), or for comparison of different phenotypes (i.e. proliferative vs. non- proliferative).

Microbiome Informatics Core Facility

In support of the computational analysis needs of investigators, provides consultation and collaborative assistance on the collection and analysis of data derived from basic biomedical research (Bioinformatics) to clinical, outcomes, public health, and health services research (Clinical and Health Informatics). Our expertise extends from traditional sequence and genomics analysis and the analysis of data from next generation sequencing technologies, to the analysis of data derived from clinical research studies.

Recruitment and Retention Shared Facility

Serves as a one-stop shop for recruitment of participants for every study by identifying potential participants and targeting them with culturally relevant messages. Maintains a mailing database of 3.5 million Alabama residents. The core can consent, enroll, and schedule participants in studies and provide expertise recruiting minorities and women. It generates standard reports for the IRB or customized reports to suit investigator needs, provides linkage between researchers and communities, and offers retention services for follow-up data collection.

Research Implementation Education and Competencies

A comprehensive set of research education programs that focus on good clinical practices and the implementation of research involving human beings. These programs provide education and training for all members of the research team from data entry personnel, regulatory managers, study coordinators, administrators and investigators.