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Muscle inflammation susceptibility predicts THA recovery

Muscle inflammation susceptibility (MuIS) status seems to be able to predict recovery after total hip arthroplasty (THA), according to research published in the April 15 issue of the American Journal of Physiology, Endocrinology and Metabolism.

Marcas M. Bamman, Ph.D., from the University of Alabama at Birmingham, and colleagues presented the results of two integrated studies to examine local MuIS as a factor in poor recovery and long-term mobility impairment after THA. In study 1 they compared muscle inflammation and protein metabolism signaling in elective THA (15 patients) versus hip fracture/trauma (11 patients) versus nonsurgical controls (19 patients). In study 2 they compared two subgroups of patients who were characterized as MuIS(+) or MuIS(−)based on muscle expression of tumor necrosis factor-like weak inducer of apoptosis receptor.

Read the full article in the Doctor's Lounge.

Posted: May 11, 2015