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A Resource Supporting High Quality and Cost Effective Clinical Trials: The NCATS Trial Innovation Network
June 11, 2018

The scandal of poor medical research

Douglas Altman, a professor of statistics in medicine at the University of Oxford , recently died at the age of 69. He waged a long-running campaign to improve the use of statistics in medical research.

The scandal of poor medical research
June 5, 2018

Assembling a comprehensive map of the molecular changes that occur in response to movement

NIH Common Fund's Molecular Transducers of Physical Activity in Humans program aims to catalogue the biological molecules affected by exercise in people, to assemble a comprehensive map of the molecular changes that occur in response to movement and, when possible, relate these changes to the benefits of physical activity. It's getting a lot of attention.

Assembling a comprehensive map of the molecular changes that occur in response to movement
Sept. 29, 2017

Stroke patients benefit from at-home therapy video game trial based at UAB

REACT Pilot Award-winner Gittendra Uswatte PhD, professor in the College of Arts and Sciences’ Department of Psychology and associate director of the CI Therapy Research Group and Taub Therapy Clinic, has developed a video game that allows stroke patients to practice Constraint-Induced Movement therapy.

Stroke patients benefit from at-home therapy video game trial based at UAB
The Internet and social media may offer valuable support and information for people with TBI
Neurotech: Virtual clinical trials: What investigators are learning about the challenge and opportunities
Effectiveness of a timing and coordination group exercise program to improve mobility in community-dwelling older adults
Master protocols to study multiple therapies, multiple diseases, or both
Woman can move again after a breakthrough stroke treatment
Smartphones open a new world for medical researchers
TBI-induced nociceptive sensitization is regulated by histone acetylation
Biopsychosocial rehab approach may ease intense CNS pain
Physical exercise restores the generation of newborn neurons in an animal model of chronic epilepsy
Feb. 21, 2017

Monitoring gait in multiple sclerosis with novel wearable motion sensors

In this original research study, the investigators applied a novel wireless, skin-mounted, and conformal inertial sensor (BioStampRC, MC10 Inc.) to examine gait characteristics of PwMS under controlled conditions and to determine the accuracy and precision of BioStampRC in measuring gait kinematics by comparing to contemporary research-grade measurement devices.

Monitoring gait in multiple sclerosis with novel wearable motion sensors
UAB study led by REACT Co-Director Gary Cutter named by NEJM as one of the top neurology stories of 2016
Vision symptoms following concussion can limit a child’s ability to return to the classroom
Dec. 1, 2016

Stem cell therapy gives paralyzed man second chance at independence

Four days after undergoing major surgery, 21-year-old Kris Boesen picked up a smartphone and sent a text. It was the first message that he had sent in months. What was truly remarkable was that Kris once almost completely paralyzed was holding a phone at all.

Stem cell therapy gives paralyzed man second chance at independence
Robot exoskeletons march in to link mind and body
Aug. 23, 2016

Emerging relationships between exercise, sensory nerves, and neuropathic pain

In this original research study, the authors encourage clinicians and researchers to continue to examine and highlight the myriad of benefits which exercise provides. and that future research should continue to examine the use of exercise in a clinical setting, looking to answer what changes occur in different neural compartments that underlie reductions in pain.

Emerging relationships between exercise, sensory nerves, and neuropathic pain
Aug. 22, 2016

Stem cell therapy heals injured mouse brain

Scientists and clinicians have long dreamed of helping the injured brain repair itself by creating new neurons, and an innovative NIH-funded study published today in Nature Medicine may bring this goal much closer to reality. A team of researchers has developed a therapeutic technique that dramatically increases the production of nerve cells in mice with stroke-induced brain damage.

Stem cell therapy heals injured mouse brain
July 18, 2016

Cardiac rehab saves lives. So why don't more heart patients sign up?

When Mario Oikonomides was 38 years old he had a massive heart attack. About a month later, after he'd recuperated from the emergency, his doctors sent him to a cardiac rehabilitation program, where he learned about the role physical activity can play in reducing cardiac risk.

Cardiac rehab saves lives. So why don't more heart patients sign up?
In-hospital mobility program proves successful for patients’ posthospital function
For people with disabilities, new technology can be life changing
April 11, 2016

A Fitbit saved his life? Well, maybe

You may already know that electronic fitness trackers can let you keep records on your smartphone of how many steps you've walked, how much you've slept, maybe your heart rate, or even where you've been. But what can the gadget tell your doctor? A few things that are pretty useful, it turns out.

A Fitbit saved his life? Well, maybe
The benefits of intensive cardiac rehabilitation over ordinary cardiac rehabilitation
Feb. 22, 2016

We all know exercise makes you live longer. But this will actually get you off the couch.

When someone dies in the intensive care unit, the first thing the nurse does is turn off the EKG monitor. That’s because the heart can go on depolarizing — writing its electrical signature on the screen, if not actually pumping blood — for many minutes after everything else stops. Because the heart is the soldier who can’t bear to surrender until long after the battle is lost.

We all know exercise makes you live longer. But this will actually get you off the couch.
Feb. 17, 2016

Which type of exercise is best for the brain?

Some forms of exercise may be much more effective than others at bulking up the brain, according to a remarkable new study in rats. For the first time, scientists compared head-to-head the neurological impacts of different types of exercise: running, weight training and high-intensity interval training.

Which type of exercise is best for the brain?
Ten-year-old concussed patient participates in research to identify biomarkers in mild traumatic brain injuries
Nov. 23, 2015

Trial combining exercise and a drug may help seniors muscle up

A drug that might help older adults regrow muscle is under investigation at the University of Alabama at Birmingham. UAB is recruiting healthy adults age 65 and older for a study combining strength training exercise with the anti-diabetes drug metformin.

Trial combining exercise and a drug may help seniors muscle up
May 18, 2015

First patient-led research registry for arthritis patients launched

CreakyJoints , an online, nonprofit, patient support community with more than 80,000 members, has launched Arthritis Power, the first patient-led, patient-generated, patient-centered research registry for arthritis, bone, and inflammatory skin conditions.

First patient-led research registry for arthritis patients launched
May 11, 2015

Muscle inflammation susceptibility predicts THA recovery

Muscle inflammation susceptibility status seems to be able to predict recovery after total hip arthroplasty, according to research published in the April 15 issue of the American Journal of Physiology, Endocrinology and Metabolism.

Muscle inflammation susceptibility predicts THA recovery
DOD grant to fund UAB rehabilitation therapy for wounded warriors
Jan. 24, 2014

High-intensity strength training shows benefit for Parkinson's patients

Researchers at the University of Alabama at Birmingham say that high-intensity strength training produced significant improvements in quality of life, mood and motor function in older patients with Parkinson’s disease. The findings were published Jan. 9 online in the Journal of Applied Physiology.

High-intensity strength training shows benefit for Parkinson's patients