Clinical Lectures, Vignettes & Courses

REACT is proud to offer online coursework to support research in medical rehabilitation. We are constantly adding to our library of courses, so please tell us if there a topic you’d like for us to discuss. You can also access these videos through our REACT Center YouTube Channel. For more information, please contact us.

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While each video is open to anyone, the following is a key to a potential audience for each presentation:

C = Clinicians P = Patients R = Researchers S = Staff

CME Podcasts

UAB MedCast is an ongoing medical education podcast. The UAB division of continuing education designates that each episode of this enduring material is worth a maximum of 0.25 AMA PRA category 1 credit.

Spinal Cord Injury

Amie McLain

Amie McLain, MD, Chair & Professor, Physical Medicine & Rehabilitation Medical Director UAB Spinal Cord Injury Model System

In this segment Dr. McLain discusses spinal cord injury, treatment options available at UAB Medicine and when to refer to a specialist.

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Rehabilitation in TBI/SCI

Candace Floyd

Candace Floyd, PhD, Associate Professor, Department of Physical Medicine and Rehabilitation

In this segment, Dr. Floyd explains the UAB Traumatic Brain Injury Model System (UAB-TBIMS) that maintains an information network to promote knowledge in research, health, and quality of life for people with TBI, their families, and TBI-related professionals.

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Clinical Trials Overview

36:41

Adherence: You Can't Improve What You Can't Measure

Jeff Curtis, MD, MS, MPH, UAB

Overview of definitions of adherence, methods to measure and comparison between methods, outcomes and improving adherence.

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39:20

Before You Begin Research: What You Must Know

Penny Jester, PhD, Program Director, UAB Clinical Trials Office UAB Research/Pediatric Virology

Considerations for planning a research clinical trial.

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31:07

ClinicalTrials.gov: What You Need to Know

Penny Jester, PhD, Program Director, UAB Clinical Trials Office UAB Research/Pediatric Virology

Background on the history of ClinicalTrials.gov and how to navigate it for your trial.

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35:50

Conceptual Models and Behavioral Frameworks in Adherence

Rivet Amico, PhD, Associate Professor, University of Michigan

"A pragmatic interventionalist's approach" to conceptual models and behavioral frameworks in adherence.

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34:01

Creating Budgets: The Basics

Tina Ayers, BS, CCRP Program Manager, Nephrology Transplant Clinical Research University of Alabama at Birmingham

Overview of study protocol and design, schema, and budget, including negotiation, management and reimbursement.

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2:55

Cultural Issues in Medication Adherence Disparities and Directions

Elizabeth McQuaid, PhD, ABPP, Alpert Medical School, Brown University

Evidence for patterns of medication use across racial/ethnic groups, barriers to consistent adherence, and strategies to overcome them.

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23:23

Drug Accountability in the Research Arena

Brenda Reed Denson, PharmD, Children's of Alabama

Discussing components for research medication documentation, required documentation and consideration of special circumstances.

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1:48

Exercise and Sleep Dysfunction

Amy Amara, MD, PhD, Assistant Professor, UAB Dept. of Neurology

A closer look at a clinical trial studying exercise as an intervention in Parkinson's patients suffering from sleep dysfunction.

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5:10

Exercise as Medicine: A UAB Approach

Ray Watts, President and Neurologist and Marcas Bamman, PHD, UCEM and REACT Director

Overview of clinical trials at UAB featuring exercise as medicine.

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58:34

Exercise Is Regenerative Medicine: Impact on Chronic Disease

Marcas Bamman, PHD, UCEM and REACT Director

Discussing how evidence-based research in exercise medicine is driving improvements in clinical care.

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57:36

Getting Your Clinical Research Funded: Everything You Always Wanted to Know About the DoD but Didn't Know Who to Ask

Robin Levin, MD, MBA, Scientific Review Officer, Peer Review and Science Management, SRA International

Overview.

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39:48

Health Behavior Research

Kathleen Harrington, PhD, MPH Associate Professor, School of Medicine UAB

Basic theories of health behavior, including behavioral factors, uses of health behavior research, and health behavior research study design, and comparison of behavioral vs. medical intervention.

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1:45

Imaging to Understand Chronic Exercise and Impact

Kimberly Wood, PhD, Neurology Research Fellow

A closer look at a clinical trial using brain imaging to collect data on the impact of chronic exercise in Parkinson's Disease.

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1:00:04

Incorporating Prehabilitation in Pre-Operative Care for Veterans

Melanie Morris, MD, Assistant Professor of Surgery at the University of Alabama at Birmingham

Overview of prehabilitation, readmission following surgery, and results to date of pilot project.

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18:14

Informed Consent

Tiffany Grimes, RN, BSN Research Nurse Coordinator CCTS and CRSP

The ins and outs of why informed consent is so important, including consent process versus document, hindrances to informed consent, and opportunities for improvement.

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1:26:14

IRB Process

Nancy Stansfield, RN, MSN, CIP, the University of Alabama at Birmingham

Review of human subjects research protections and the process by which research is vetted to ensure human subjects protections.

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32:02

Managing a Study

Bari Cotton, RN, BA, MA SAE/PD Coordinator for the Collaborative Antiviral Study Unit Research Nurse Coordinator

Explanation of key startup activities, time management, and working with ancillary departments.

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26:56

Monitoring and Audits

Meredith Fitz-Gerald, RN, MSN CCTS Nurse Research Manager at UAB

Overview of clinical trials monitoring, types of monitoring, and review of regulations governing monitoring.

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47:01

Optimizing Rehabilition After Total Knee Replacement in a Changing Healthcare Arena

Jennifer Stevens-Lapsley, PT, PhD, Professor Physical Therapy, University of Colorado

Discusses translating rehabilitation work from a research setting to real-world clinical practice.

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24:33

Organizational Codes of Conduct and Conflicts of Interest in Research

Katie Crenshaw, University Compliance Coordinator, UAB

Overview of research codes of conduct, common elements, what conflicts are, and ways to meet code of conduct expectations.

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26:49

Patient-Centered Medication Adherence Research: Research Done Differently

Penny Mohr, MA, Senior Project Officer, Patient Centered Outcomes Research Initiative

PCORI researcher discusses comparative effectiveness trials and medication adherence from the patient perspective.

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1:04:08

Physical Activity and Multiple Sclerosis: What We've Learned

Robert Motl, PhD, REACT Mobile Technology Laboratory Director, Professor, UAB School of Health Professions

Overview of research into how physical activity can be used and tested in the multiple sclerosis patient.

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59:00

Pre-Study Activities, Where Do I Start?

Carla Perna, Administrative Director, REACT Center, MR3 Network, UAB Center for Exercise Medicine

Overview of considerations and activities that should take place before starting a clinical trial.

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1:03:27

Prevention and Treatment of Missing Data in Clinical Trials

Scott Emerson, MD, PhD, Professor of Biostatistics, University of Washington

Overview of the various estimates that might be addressed in a clinical trial so as to account for the eventuality of missing data; an approach to defining sensitivity analyses that first defines a missing at random (MAR) mechanism, and then explores a spectrum of departures that encompass relevant missing not at random (MNAR) models.

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6:00

Quality Assurance, Quality Control, and Management of CRFs and Source Documents

Karen Savage, RN, CCRC, UAB

Definition of source documents (eg. case report forms), creating completing, and managing case report forms.

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41:37

Recruitment and Retention

Joey Richardson, RN, CCRC, UAB

Identification of common recruitment/retention barriers, and advertising guidelines for recruitment of participants.

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31:19

Regulatory Document Management

Susan Branscum, CCRP, UAB Regulatory Manager

Introduction to essential regulatory documents required to conducted a clinical trial and the sources requiring these documents.

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48:10

Research Training Program

Shelia Moore, BS, Director of Clinical Studies, Birmingham VA Medical Center

General overview of human subjects research and an explanation of the human subjects research process.

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38:58

Serious Adverse Event Reporting

Leigh Powell, MSN, BSN, RN, CCRC, Research Nurse Coordinator, UAB

Review purpose of clinical trial serious adverse event reporting process and procedures.

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7:55

So You Want to Design a Clinical Trial

Gary Cutter, PhD, Co-Director, REACT, Professor of Biostatistics, University of Alabama at Birmingham

Review introductory concepts of clinical trials; purpose, design, implementation and evaluation along with examples and controversies of clinical trial design.

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17:57

Study Closeout

Tiffany Grimes, RN, BSN, Research Nurse Coordinator, UAB CCTS

Review purpose of clinical trial closeout process and procedures to close a study.

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Clinical Trials Design

31:01

Adherence: An NIH Perspective

Michael Stirratt, PhD, NIMH Division of AIDS Research

An NIH researcher discusses treament adherence in clinical trials; includes discussion on NIH Adherence Network.

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1:07:55

Comparative Effectiveness Research and Patient-Centered Outcomes Research: T2 Research and Beyond

Kenneth Saag, MD, MSC, Director, REACT Promotion & Dissemination

Overview of T2 Research, domains of comparative effectiveness research (CER) and patient cetnered outcomes research (PCOR).

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1:19:09

Design of Pilot Studies

David Redden, PhD, Professor, Biostatistics, UAB School of Public Health

Overview of how to design a pilot study from a biostatistics point of view.

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23:39

Introduction to Device Studies

Cynthia Joiner, PhD, MPH, MSN, RN Assistant Professor, Cardiovascular Disease

Overview of clinical trials using medical devices including defining devices, the regulatory pathway, and nuances of device studies.

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11:43

Life-Space Assessment

Cynthia Brown, PT, MD, MSPH, REACT Coinvestigator

Examine mobility and LSA. Use the WHO International Classification of Functioning. Provide an overview of the concepts of activities and participation. Describe methods for measuring these two domains including the UAB Study of Aging LSA.

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41:03

Method for Testing/Training Cardiorespiratory Fitness of Individuals with Gait and Balance Disability

Christopher Hurt, PhD Assistant Professor, UAB Department of Physical Therapy

Describing a novel way to deliver exercise testing and training for an individual's gait and balance disabilities, demonstrating validation data on the training method, presenting a new device to deliver exercise training.

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44:30

Pitfalls in RRMS and Progressive Clinical Trials in MS

Gary Cutter, PhD, Co-Director, REACT, Professor of Biostatistics, University of Alabama at Birmingham

Overview of pragmatic clinical trial study design.

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6:50

Pragmatic Clinical Trials

Kenneth Saag, MD, MSC, Director, REACT Promotion & Dissemination

Review introductory concepts of clinical trials; purpose, design, implementation and evaluation along with examples and controversies of clinical trial design.

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Incorporation of Biologic Mechanisms into Clinical Trials

12:48

Inter-individual Response Heterogeneity

Marcas Bamman, PHD, REACT Director

Overview of inter-individual response heterogeneity in rehabilitation trials, examples of participant responses, and understanding what the respones mean.

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15:06

mHealth, PROS, and Biosensors

James Curtis, MD, MPH, REACT Collaborator

Overview of mobile health, patient reported outcomes, and biosensors and their use in rehabilitation research.

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52:26

Remarkable Anti-Aging Effects of Aerobic Exercise on Arteries

Douglas Seals, PhD, University of Colorado, Boulder Department of Integrative Physiology UCEM Distinguished Lecture Series

Lecture on study of role of aerobic exercise on vascular aging, with details on large elastic artery function, endothelial function, and vascluar protection.

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13:11

Shake Algorithm vs. Smartphone Pedometers

James Willig, PhD, PhD, REACT Collaborator

Performance of the shake algorithm versus the pedometers found in smartphones for accuracy in clinical trials.

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13:26

Tools to Investigate Sleep in Rehabilitation Research

Amy Amara, MD, PhD

A review of how sleep can be very useful in evaluating outcomes related to rehabilitation research.

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11:26

Walking as Important Outcome in Medical Rehabilitation Research

Robert Motl, PhD, REACT Mobile Technology Laboratory Director, Professor, UAB School of Health Professions

A closer look at the importance of walking as a measurable outcome in medical rehab research.

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